Entity Central Index Key
Cover [Abstract]
Document Type
Document Type
Document Annual Report
Document Annual Report
Document Period End Date
Document Period End Date
Document Transition Report
Document Transition Report
Entity File Number
Entity File Number
Entity Registrant Name
Entity Registrant Name
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, Address Line Two
Entity Address Address Line2
Entity Address, City or Town
Entity Address City Or Town
Entity Address, State or Province
Entity Address State Or Province
Entity Address, Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Title of 12(b) Security
Security12b Title
Trading Symbol
Trading Symbol
Security Exchange Name
Security Exchange Name
Entity Current Reporting Status
Entity Current Reporting Status
Entity Interactive Data Current
Entity Interactive Data Current
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Ex Transition Period
Entity Ex Transition Period
Entity Shell Company
Entity Shell Company
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Amendment Flag
Amendment Flag
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Central Index Key
Entity Voluntary Filers
Entity Voluntary Filers
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Public Float
Entity Public Float
Preferred stock purchase right liability.
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Short-term investments, available-for-sale
Available For Sale Securities Debt Securities Current
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Total current assets
Assets Current
Restricted cash
Restricted Cash Noncurrent
Property and equipment, net
Property Plant And Equipment Net
Operating lease right-of-use assets
Operating Lease Right Of Use Asset
Other long-term assets
Other Assets Noncurrent
Total assets
Assets
Liabilities, convertible preferred stock and stockholders' equity (deficit)
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Operating lease liabilities, current portion
Operating Lease Liability Current
Preferred stock purchase right liability
Preferred Stock Purchase Right Liability
Accrued and other current liabilities
Accrued Liabilities Current
Total current liabilities
Liabilities Current
Operating lease liabilities, net of current portion
Operating Lease Liability Noncurrent
Other long-term liabilities
Other Liabilities Noncurrent
Total liabilities
Liabilities
Commitments and contingencies (Note 7)
Commitments And Contingencies
Convertible preferred stock, $0.0001 par value; no shares and 54,350,179 shares authorized at December 31, 2020 and 2019, respectively; no shares and 27,283,973 shares issued and outstanding at December 31, 2020 and 2019, respectively
Temporary Equity Carrying Amount Attributable To Parent
Stockholders' equity (deficit):
Stockholders Equity [Abstract]
Preferred stock, $0.0001 par value; 54,350,179 shares and no shares authorized at December 31, 2020 and 2019, respectively; no shares issued and outstanding at December 31, 2020 and 2019
Preferred Stock Value
Common stock, $0.0001 par value; 100,000,000 and 71,919,982 shares authorized at December 31, 2020 and 2019, respectively; 32,627,963 and 1,600,601 shares issued and outstanding at December 31, 2020 and 2019, respectively
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income Loss Net Of Tax
Accumulated deficit
Retained Earnings Accumulated Deficit
Total stockholders' equity (deficit)
Stockholders Equity
Total liabilities, convertible preferred stock and stockholders' equity (deficit)
Liabilities And Stockholders Equity
Convertible preferred stock, par value
Temporary Equity Par Or Stated Value Per Share
Convertible preferred stock, shares authorized
Temporary Equity Shares Authorized
Convertible preferred stock, shares issued
Temporary Equity Shares Issued
Convertible preferred stock, shares outstanding
Temporary Equity Shares Outstanding
Preferred stock, par value
Preferred Stock Par Or Stated Value Per Share
Preferred stock, shares authorized
Preferred Stock Shares Authorized
Preferred stock, shares issued
Preferred Stock Shares Issued
Preferred stock, shares outstanding
Preferred Stock Shares Outstanding
Common stock, par value
Common Stock Par Or Stated Value Per Share
Common stock, shares authorized
Common Stock Shares Authorized
Common stock, shares issued
Common Stock Shares Issued
Common stock, shares outstanding
Common Stock Shares Outstanding
Change in fair value of derivative liability.
Non-cash interest expense on convertible notes.
Income Statement [Abstract]
Collaboration revenue
Revenue From Contract With Customer Excluding Assessed Tax
Operating expenses:
Operating Expenses [Abstract]
Research and development
Research And Development Expense
General and administrative
General And Administrative Expense
Total operating expenses
Operating Expenses
Loss from operations
Operating Income Loss
Other income (expense), net:
Nonoperating Income Expense [Abstract]
Change in fair value of preferred stock purchase right liability
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Gain Loss Included In Earnings
Change in fair value of derivative liability
Change In Fair Value Of Derivative Liability
Loss from extinguishment of debt
Gains Losses On Extinguishment Of Debt
Interest income
Investment Income Net
Interest expense
Non Cash Interest Expense On Convertible Notes
Other income (expense), net
Other Nonoperating Income Expense
Total other income (expense), net
Nonoperating Income Expense
Net loss
Net Income Loss
Comprehensive loss:
Comprehensive Income Net Of Tax [Abstract]
Net loss
Other comprehensive loss:
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent [Abstract]
Unrealized loss on securities
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
Comprehensive loss
Comprehensive Income Net Of Tax
Net loss per share, basic and diluted
Earnings Per Share Basic And Diluted
Weighted-average number of common shares used in net loss per share, basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Temporary equity beneficial conversion feature upon issuance of convertible.
Temporary equity, reacquisition of beneficial conversion feature upon settlement of promissory notes.
Temporary equity stock issued during period shares upon conversion of promissory notes.
Temporary equity stock issued during period value upon conversion of promissory notes.
Temporary equity stock issued during period shares new issues.
Temporary equity, preferred stock purchase right (liability) reversal upon issuance of convertible securities.
Stock issued during period value vesting of shares of common stock subject to repurchase.
Stock issued during period shares vesting of shares of common stock subject to repurchase.
Temporary equity reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock.
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Class of Stock
Statement Class Of Stock [Axis]
Class of Stock
Class Of Stock [Domain]
Convertible Preferred Stock
Convertible Preferred Stock [Member]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock
Common Stock [Member]
Additional Paid-In Capital
Additional Paid In Capital [Member]
Accumulated Deficit
Retained Earnings [Member]
Accumulated Other Comprehensive Loss
Accumulated Other Comprehensive Income [Member]
Statement [Line Items]
Statement [Line Items]
Temporary Equity, Beginning Balance, Shares
Temporary Equity, Beginning Balance
Beginning Balance, Shares
Shares Outstanding
Beginning Balance
Temporary equity, beneficial conversion feature upon issuance of convertible
Temporary Equity Beneficial Conversion Feature Upon Issuance Of Convertible
Temporary equity, reacquisition of beneficial conversion feature upon settlement of promissory notes
Temporary Equity Reacquisition Of Beneficial Conversion Feature Upon Settlement Of Promissory Notes
Temporary equity, issuance of Series B convertible preferred stock upon conversion of promissory notes
Temporary Equity Stock Issued During Period Value Upon Conversion Of Promissory Notes
Temporary equity, issuance of Series B convertible preferred stock upon conversion of promissory notes, Shares
Temporary Equity Stock Issued During Period Shares Upon Conversion Of Promissory Notes
Temporary equity, Issuance of Series B convertible preferred stock, net of issuance costs
Temporary Equity Stock Issued During Period Value New Issues
Temporary equity, Issuance of Series B convertible preferred stock, net of issuance costs, Shares
Temporary Equity Stock Issued During Period Shares New Issues
Temporary equity, series B preferred stock purchase right (liability) upon issuance of Series B convertible preferred stock
Temporary Equity Preferred Stock Purchase Right Liability Reversal Upon Issuance Of Convertible Securities
Reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock
Temporary Equity Reclassification Of Preferred Stock Purchase Right Liability To Equity Upon Issuance Of Convertible Preferred Stock
Temporary equity, conversion of convertible preferred stock to common stock
Conversion Of Stock Amount Converted1
Temporary equity, conversion of convertible preferred stock to common stock, Shares
Conversion Of Stock Shares Converted1
Conversion of convertible preferred stock to common stock
Stock Issued During Period Value Conversion Of Convertible Securities
Conversion of convertible preferred stock to common stock, Shares
Stock Issued During Period Shares Conversion Of Convertible Securities
Issuance of common stock upon initial public offering, net of issuance costs
Stock Issued During Period Value New Issues
Issuance of common stock upon initial public offering, net of issuance costs, Shares
Stock Issued During Period Shares New Issues
Vesting of shares of common stock subject to repurchase
Stock Issued During Period Value Vesting Of Shares Of Common Stock Subject To Repurchase
Vesting of shares of common stock subject to repurchase, Shares
Stock Issued During Period Shares Vesting Of Shares Of Common Stock Subject To Repurchase
Issuance of common stock upon exercise of stock option, net of repurchase
Stock Issued During Period Value Stock Options Exercised
Issuance of common stock upon exercise of stock option, net of repurchase, Shares
Stock Issued During Period Shares Stock Options Exercised
Share-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Temporary Equity, Ending Balance, Shares
Temporary Equity, Ending Balance
Ending Balance, Shares
Ending Balance
Non cash interest expense.
Increase (Decrease) in accounts payable and accrued and other liabilities.
Proceeds from issuance of convertible preferred stock, net of issuance costs.
Proceeds from early exercise of stock options.
Deferred offering costs included in accounts payable and accrued liabilities.
Statement Of Cash Flows [Abstract]
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Net loss
Profit Loss
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Share-based compensation expense
Share Based Compensation
Depreciation and amortization expense
Depreciation And Amortization
Accretion of discount and amortization of premium on investments, net
Accretion Amortization Of Discounts And Premiums Investments
Non-cash lease expense
Operating Lease Right Of Use Asset Amortization Expense
Change in fair value of preferred stock purchase right liability
Change in fair value of derivative liability
Derivative Gain Loss On Derivative Net
Non-cash loss from extinguishment of debt
Non-cash interest expense
Non Cash Interest Expense
Others
Other Noncash Income Expense
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Prepaid expenses and other assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Accounts payable and accrued and other liabilities
Increase Decrease In Accounts Payable And Accrued And Other Liabilities
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
Purchases of available-for-sale securities
Payments To Acquire Available For Sale Securities Debt
Proceeds from maturities of available-for-sale securities
Proceeds From Maturities Prepayments And Calls Of Available For Sale Securities
Purchase of property and equipment
Payments To Acquire Property Plant And Equipment
Net cash used in investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from issuance of convertible preferred stock, net of issuance costs
Proceeds From Issuance Of Convertible Preferred Stock Net Of Issuance Costs
Proceeds from initial public offering, net of issuance costs
Proceeds From Issuance Initial Public Offering
Proceeds from stock option exercises
Proceeds From Stock Options Exercised
Proceeds from early exercise of stock options
Proceeds From Early Exercise Of Stock Options
Proceeds from issuance of convertible notes, net of issuance costs
Proceeds From Convertible Debt
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
Net increase in cash and cash equivalents
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Cash, cash equivalents and restricted cash at beginning of year
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
Cash, cash equivalents and restricted cash at end of year
Reconciliation of cash, cash equivalents and restricted cash to the balance sheets:
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents [Abstract]
Restricted cash
Restricted Cash
Total cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
Supplemental disclosures of non-cash investing and financing activities:
Supplemental Cash Flow Information [Abstract]
Acquisitions of property and equipment
Noncash Or Part Noncash Acquisition Fixed Assets Acquired1
Deferred offering costs included in accrued and other current liabilities
Deferred Offering Costs Included In Accounts Payable And Accrued Liabilities
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Description of Business
Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block]
Accounting Policies [Abstract]
Basis of Presentation and Significant Accounting Policies
Significant Accounting Policies [Text Block]
Earnings Per Share [Abstract]
Net Loss Per Share
Earnings Per Share [Text Block]
Fair Value Disclosures [Abstract]
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Balance Sheet Related Disclosures [Abstract]
Balance Sheet Components
Supplemental Balance Sheet Disclosures [Text Block]
Leases [Abstract]
Leases
Lessee Operating Leases [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
License agreement.
License agreement.
License Agreement [Abstract]
University of Singapore and St. Jude Children’s License Agreement
License Agreement [Text Block]
Compensation And Retirement Disclosure [Abstract]
Employee Benefits
Compensation And Employee Benefit Plans [Text Block]
Equity [Abstract]
Convertible Preferred Stock and Stockholders’ Equity (Deficit)
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Share-Based Compensation
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Basis of Presentation
Basis Of Accounting Policy Policy [Text Block]
Reverse stock split policy.
Reverse Stock Split
Reverse Stock Split Policy Policy [Text Block]
Unusual or infrequent items disclosure.
COVID-19 Pandemic
Unusual Or Infrequent Items Disclosure Policy [Text Block]
Use of Estimates
Use Of Estimates
Concentration of Credit Risk
Concentration Risk Credit Risk
Comprehensive Loss
Comprehensive Income Policy Policy [Text Block]
Fair Value of Financial Instruments
Fair Value Measurement Policy Policy [Text Block]
Cash cash equivalents short term investments and restricted cash.
Cash, Cash Equivalents, Short-term Investments and Restricted Cash
Cash Cash Equivalents Short Term Investments And Restricted Cash Policy [Text Block]
Property and Equipment, Net
Property Plant And Equipment Policy [Text Block]
Impairment of Long-Lived Assets
Impairment Or Disposal Of Long Lived Assets Policy [Text Block]
Deferred Offering Costs
Deferred Charges Policy [Text Block]
Preferred stock purchase right liability.
Preferred Stock Purchase Right Liability
Preferred Stock Purchase Right Liability Policy [Text Block]
Temporary equity.
Convertible Preferred Stock
Temporary Equity Policy [Text Block]
Revenue Recognition
Revenue From Contract With Customer Policy [Text Block]
Research and Development Costs
Research And Development Expense Policy
Commitments
Commitments And Contingencies Policy [Text Block]
Leases
Lessee Leases Policy [Text Block]
Share-Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Income Taxes
Income Tax Policy [Text Block]
Segment Reporting
Segment Reporting Policy Policy [Text Block]
Net Loss Per Share
Earnings Per Share Policy [Text Block]
Recent Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Computation of Basic and Diluted Net Loss Per Share
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Summarizes the Outstanding Potentially Dilutive Securities Excluded in Calculation of Diluted Net Loss Per Share
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Investment Type
Investment Type [Axis]
Investments
Investment Type Categorization [Member]
Short-term investments
Short Term Investments [Member]
Summary of Fair Value of Financial Instrument
Fair Value By Balance Sheet Grouping [Text Block]
Schedule of Short-term Investments
Debt Securities Available For Sale Table [Text Block]
Schedule of Change in Preferred Stock Purchase Right Liability
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Text Block]
Schedule of prepaid expenses and other current assets.
Schedule of Prepaid Expenses and Other Current Assets
Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block]
Schedule of Property and Equipment, Net
Property Plant And Equipment [Text Block]
Schedule of Accrued and Other Current Liabilities
Schedule Of Accounts Payable And Accrued Liabilities Table [Text Block]
Components of Lease Expense
Lease Cost Table [Text Block]
Schedule of supplemental information related to operating leases.
Schedule of Supplemental Information related to Operating Leases
Schedule Of Supplemental Information Related To Operating Leases Table [Text Block]
Schedule of Maturities of Operating Lease Liabilities
Lessee Operating Lease Liability Maturity Table [Text Block]
Summary of Stock Option Activity
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Schedule of share based compensation additional information related to stock options.
Summary of Additional Information Related to Stock Options
Schedule Of Share Based Compensation Additional Information Related To Stock Options
Summary of common stock reserved for future issuance.
Summary of Common Stock Reserved For Future Issuance
Summary Of Common Stock Reserved For Future Issuance Table [Text Block]
Summary of Share-based Compensation Expense
Schedule Of Compensation Cost For Share Based Payment Arrangements Allocation Of Share Based Compensation Costs By Plan Table [Text Block]
Schedule of Fair Value of Stock Options Estimated on Date of Grant Using Black-Scholes Option Pricing Model
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Reconciliation on Income Taxes Amount Computed by Applying Statutory Federal Income Tax Rate to Net Loss
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Significant Components of Deferred Tax Assets
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Summary of Changes in Gross Unrecognized Tax Benefits
Schedule Of Unrecognized Tax Benefits Roll Forward Table [Text Block]
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
IPO
I P O [Member]
Underwriters Option to Purchase Additional Shares
Over Allotment Option [Member]
Series B convertible preferred stock.
Series B Convertible Preferred Stock
Series B Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Class Of Stock [Line Items]
Number of operating segments
Number Of Operating Segments
Shares issued during period
Shares issued, price per share
Shares Issued Price Per Share
Conversion of convertible preferred stock to common stock
Net proceeds after deducting underwriting discounts,commissions and other offering costs
Cash cash equivalents restricted cash and short term investments.
Accumulated deficit
Cash, cash equivalents, restricted cash and short-term investments
Cash Cash Equivalents Restricted Cash And Short Term Investments
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs
Proceeds From Issuance Of Convertible Preferred Stock
Temporary equity, shares issued
Accounting policies.
Accounting policies.
Accounting Policies [Table]
Accounting Policies [Table]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Minimum
Minimum [Member]
Maximum
Maximum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
Collaboration and license agreement.
Collaboration and License Agreement
Collaboration And License Agreement [Member]
Counterparty Name
Counterparty Name [Axis]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
GlaxoSmithKline Intellectual Property Development Limited and Glaxo Group Limited.
GSK
Glaxo Smith Kline Intellectual Property Development Limited And Glaxo Group Limited [Member]
Accounting Standards Update
Adjustments For New Accounting Pronouncements [Axis]
Accounting Standards Update
Type Of Adoption [Member]
ASU 2016-13
Accounting Standards Update201613 [Member]
ASU 2018-13
Accounting Standards Update201813 [Member]
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Reverse stock split, conversion ratio
Stockholders Equity Note Stock Split Conversion Ratio1
Description of the reverse stock split
Stockholders Equity Reverse Stock Split
Estimated useful lives of assets
Property Plant And Equipment Useful Life
Impairment losses on long-lived assets
Impairment Of Long Lived Assets Held For Use
Deferred offering costs
Deferred Offering Costs
Outstanding shares
Product revenue
Liability regard to loss contingencies
Loss Contingency Accrual At Carrying Value
Contractual term of options granted
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change In Accounting Principle Accounting Standards Update Adopted
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change In Accounting Principle Accounting Standards Update Adoption Date
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change In Accounting Principle Accounting Standards Update Immaterial Effect
Weighted average number of shares unvested common stock issued upon early exercise of common stock options.
Weighted average number of shares unvested founder shares of common stock.
Numerator:
Net Income Loss [Abstract]
Denominator:
Weighted Average Number Of Shares Outstanding [Abstract]
Weighted average common shares outstanding
Weighted Average Number Of Shares Issued Basic
Less: weighted average unvested common stock issued upon early exercise of common stock options
Weighted Average Number Of Shares Unvested Common Stock Issued Upon Early Exercise Of Common Stock Options
Less: weighted average unvested founder shares of common stock
Weighted Average Number Of Shares Unvested Founder Shares Of Common Stock
Weighted average shares used to compute net loss per share, basic and diluted
Net loss per share, basic and diluted
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Common stock options.
Common Stock Options
Common Stock Options [Member]
Unvested common stock upon early exercise of common stock options.
Unvested Common Stock Upon Early Exercise of Common Stock Options
Unvested Common Stock Upon Early Exercise Of Common Stock Options [Member]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Preferred stock purchase right liability fair value disclosure.
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Abstract]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Quoted Prices in Active Markets for Identical Assets (Level 1)
Fair Value Inputs Level1 [Member]
Significant Other Observable Inputs (Level 2)
Fair Value Inputs Level2 [Member]
Significant Unobservable Inputs (Level 3)
Fair Value Inputs Level3 [Member]
Financial Instrument
Financial Instrument [Axis]
Financial Instruments
Transfers And Servicing Of Financial Instruments Types Of Financial Instruments [Domain]
Corporate Debt Securities
Corporate Debt Securities [Member]
U.S. Government Securities
U S Government Agencies Debt Securities [Member]
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Commercial Paper
Commercial Paper [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Assets:
Assets Fair Value Disclosure [Abstract]
Money market funds
Money Market Funds At Carrying Value
Total short-term investments
Short Term Investments
Total
Assets Fair Value Disclosure
Liabilities:
Liabilities Fair Value Disclosure [Abstract]
Preferred stock purchase right liability
Preferred Stock Purchase Right Liability Fair Value Disclosure
Commercial paper
Commercial Paper At Carrying Value
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table]
Money Market Funds
Money Market Funds [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Investments
Cash And Cash Equivalents Fair Value Disclosure
U.S. Government Securities
U S Government Corporations And Agencies Securities [Member]
Available for sale securities, Amortized Cost
Available For Sale Debt Securities Amortized Cost Basis
Available for sale securities, Unrealized Losses
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Available for sale securities, Unrealized Gains
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
Available for sale securities,Estimated Fair Value
Available For Sale Securities Debt Securities
Available-for-sale securities, Maturity (in years)
Debt Securities Available For Sale Term
Impairments.
Impairments
Impairments
Realized gain or loss on available-for-sale securities
Debt Securities Available For Sale Realized Gain Loss
Accrued interest receivable
Interest Receivable Current
Proceeds from issuance of convertible preferred stock
Fair value of preferred stock purchase right liability percentage.
Fair value of preferred stock purchase right liability discount rate.
Fair value of preferred stock purchase right liability outstanding term.
Fair value of preferred stock purchase right liability percentage
Fair Value Of Preferred Stock Purchase Right Liability Percentage
Fair value of preferred stock purchase right liability discount rate
Fair Value Of Preferred Stock Purchase Right Liability Discount Rate
Fair value of preferred stock purchase right liability outstanding term
Fair Value Of Preferred Stock Purchase Right Liability Outstanding Term
Fair value measurement with unobservable inputs reconciliations Reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock.
Fair Value Assets And Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Abstract]
Balance, December 31, 2019
Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Value
Reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock
Fair Value Measurement With Unobservable Inputs Reconciliations Reclassification Of Preferred Stock Purchase Right Liability To Equity Upon Issuance Of Convertible Preferred Stock
Balance, December 31, 2020
Prepaid expenses
Prepaid Expense Current
Other current assets
Other Assets Current
Total prepaid expenses and other current assets
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Leasehold Improvements
Leasehold Improvements [Member]
Furniture and Fixtures
Furniture And Fixtures [Member]
Research equipment.
Research Equipment
Research Equipment [Member]
Computers and software.
Computers and Software
Computers And Software [Member]
Construction in Progress
Construction In Progress [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Total property and equipment
Property Plant And Equipment Gross
Less accumulated depreciation and amortization
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Total property and equipment, net
Depreciation and amortization expense
Depreciation Depletion And Amortization
Accrued research and development costs current.
Accrued property and equipment liabilities current.
Deferred offering costs liabilities current.
Accrued compensation
Employee Related Liabilities Current
Accrued research and development costs
Accrued Research And Development Costs Current
Accrued property and equipment
Accrued Property And Equipment Liabilities Current
Deferred offering costs
Deferred Offering Costs Liabilities Current
Other accrued and current liabilities
Accounts Payable And Other Accrued Liabilities Current
Total accrued and other liabilities
Accounts Payable And Accrued Liabilities Current
Lease, Cost [Abstract]
Lease Cost [Abstract]
Operating lease expense
Operating Lease Cost
Variable lease expense
Variable Lease Cost
Short-term lease expense
Short Term Lease Cost
Total lease expense
Lease Cost
Cash paid for amounts included in the measurement of lease liabilities.
Lease liabilities arising from obtaining right-of-use assets
Cash paid for amounts included in the measurement of lease liabilities
Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract]
Operating cash flows used for operating leases
Operating Lease Payments
Lease liabilities arising from obtaining right-of-use assets
Lease Liabilities Arising From Obtaining Right Of Use Assets [Abstract]
Operating leases
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
Lessee Lease Description [Table]
Lessee Lease Description [Table]
Corporate office and laboratory space.
Corporate Office and Laboratory Space
Corporate Office And Laboratory Space [Member]
Vivarium.
Vivarium
Vivarium [Member]
Corporate office and laboratory facilities.
Corporate Office and Laboratory Facilities
Corporate Office And Laboratory Facilities [Member]
Subsequent Event Type
Subsequent Event Type [Axis]
Subsequent Event Type
Subsequent Event Type [Domain]
Subsequent Event
Subsequent Event [Member]
Lessee Lease Description [Line Items]
Lessee Lease Description [Line Items]
Weighted-average remaining lease term
Operating Lease Weighted Average Remaining Lease Term1
Renewal term
Lessee Operating Lease Renewal Term
Operating lease, existence of option to extend
Lessee Operating Lease Existence Of Option To Extend
Weighted-average discount rate
Operating Lease Weighted Average Discount Rate Percent
2021
Lessee Operating Lease Liability Payments Due Next Twelve Months
2022
Lessee Operating Lease Liability Payments Due Year Two
2023
Lessee Operating Lease Liability Payments Due Year Three
2024
Lessee Operating Lease Liability Payments Due Year Four
2025
Lessee Operating Lease Liability Payments Due Year Five
2026 and thereafter
Lessee Operating Lease Liability Payments Due After Year Five
Total future minimum lease payments
Lessee Operating Lease Liability Payments Due
Less imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
Present value of net minimum lease payments
Operating Lease Liability
Operating lease liabilities:
Operating Lease Liability [Abstract]
Current
Non-current
Total lease liability
Lease expiration year.
Lease term
Lessee Operating Lease Remaining Lease Term
Lease expiration year
Lease Expiration Year
Lessee option to extend description
Lessee Operating Lease Option To Extend
Lease expiration month and year.
Operating lease, description
Lessee Operating Lease Description
Lease expiration month and year
Lease Expiration Month And Year
Lessee operating lease lease not yet commenced minimum lease payments.
Operating lease not yet commenced minimum lease payments
Lessee Operating Lease Lease Not Yet Commenced Minimum Lease Payments
Loss Contingencies [Table]
Loss Contingencies [Table]
Agreement with financial institution.
Agreement with Financial Institution
Agreement With Financial Institution [Member]
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Liabilities recorded for agreements
Guarantee Obligations Current Carrying Value
Letter of credit notice period by financial institution before annual expiration date.
Letters of credit outstanding amount
Letters Of Credit Outstanding Amount
Letter of credit notice period by financial institution before annual expiration date
Letter Of Credit Notice Period By Financial Institution Before Annual Expiration Date
License agreement upfront payment.
Stock issued during period shares issued upfront payments.
Annual license maintenance fee.
Potential milestone payments.
Percentage of Licensors royalties.
Percentage of sublicensing income.
License agreement term.
Fair value of common stock issued.
License agreement.
License agreement.
License Agreement [Table]
License Agreement [Table]
National University of Singapore and St. Jude Children's Research Hospital.
NUS and St. Jude
National University Of Singapore And St Jude Children S Research Hospital [Member]
License agreement.
License Agreement
License Agreement [Member]
Scenario
Statement Scenario [Axis]
Scenario
Scenario Unspecified [Domain]
After year two.
After Year Two of the Agreement
After Year Two [Member]
Product and Service
Product Or Service [Axis]
Product and Service
Products And Services [Domain]
License Maintenance Fees
License And Maintenance [Member]
License Agreement [Line Items]
License Agreement [Line Items]
Upfront payment
License Agreement Upfront Payment
Upfront payment, shares issued
Stock Issued During Period Shares Issued Upfront Payments
Fair value of common stock issued
Fair Value Of Common Stock Issued
Annual license maintenance fee
Annual License Maintenance Fee
Potential milestone payments
Potential Milestone Payments
Percentage of licensors royalties
Percentage Of Licensors Royalties
Percentage of sublicensing income
Percentage Of Sublicensing Income
License agreement term
License Agreement Term
Milestone payment upon completion of regulatory milestone related to the clinical development.
Research and development costs
Milestone payment
Milestone Payment Upon Completion Of Regulatory Milestone Related To Clinical Development
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Retirement Plan Type
Retirement Plan Type [Axis]
Retirement Plan Type
Retirement Plan Type [Domain]
401 (K) Plan.
401 (K) Plan
K Plan [Member]
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Defined contribution plan, description
Description Of Defined Contribution Pension And Other Postretirement Plans
Employer contribution, percent
Defined Contribution Plan Employer Matching Contribution Percent
Expense contribution plan
Defined Contribution Plan Cost Recognized
Series A convertible preferred stock.
Series A Convertible Preferred Stock
Series A Convertible Preferred Stock [Member]
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
Series A financing investors.
Series A Financing investors
Series A Financing Investors [Member]
Debt Instrument
Debt Instrument [Axis]
Debt Instrument, Name
Debt Instrument Name [Domain]
GlaxoSmithKline convertible note.
GSK Convertible Note
Glaxo Smith Kline Convertible Note [Member]
Series A investors.
Series A investors
Series A Investors [Member]
Series B convertible promissory notes.
Series B Convertible Promissory Notes
Series B Convertible Promissory Notes [Member]
Revision of Prior Period
Restatement [Axis]
Revision of Prior Period
Restatement [Domain]
Previously Recorded
Restatement Adjustment [Member]
Stock purchase agreement.
Stock Purchase Agreement
Stock Purchase Agreement [Member]
Capital stock, shares authorized
Capital Units Authorized
Percentage of outstanding convertible notes converted into convertible preferred stock.
Stock issued and sold
Convertible preferred stock price per share
Debt Instrument Convertible Conversion Price1
Convertible notes outstanding shares converted into convertible preferred stock
Convertible Preferred Stock Shares Issued Upon Conversion
Percentage of outstanding convertible notes into convertible preferred stock
Percentage Of Outstanding Convertible Notes Converted Into Convertible Preferred Stock
Convertible notes, beneficial conversion feature
Debt Instrument Convertible Beneficial Conversion Feature
Convertible notes accrued interest per year.
Percentage of convertible notes automatically convert into Series B convertible preferred stock.
Number of convertible promissory notes issued
Stock Issued During Period Value Conversion Of Convertible Securities Net Of Adjustments
Convertible notes accrued interest per year
Convertible Notes Accrued Interest Per Year
Convertible notes original maturity date from issuance date
Debt Instrument Term
Percentage of convertible notes automatically convert into Series B convertible preferred stock price per share
Percentage Of Convertible Notes Automatically Convert Into Series B Convertible Preferred Stock
Amortization Term of interest expense using effective interest method.
Derivative instrument
Convertible Debt Fair Value Disclosures
Amortization term of interest expense using effective interest method
Amortization Term Of Interest Expense Using Effective Interest Method
Change in conversion benefit resulted in adjustment to derivative instrument.
Change in conversion benefit resulted in adjustment to derivative instrument
Change In Conversion Benefit Resulted In Adjustment To Derivative Instrument
Loss on extinguishment of debt
Interest expense related to stated interest
Interest Expense Debt Excluding Amortization
Effective-interest relation to debt discounts
Amortization Of Financing Costs
Annual effective-interest rates
Debt Instrument Interest Rate Effective Percentage
Temporary equity stock issuable upon achievement of milestone
Gross proceeds from issuance of convertible preferred stock.
Conversion of stock shares convertible.
Number of convertible preferred stock sold and issued during the period
Temporary Equity Stock Issuable Upon Achievement Of Milestone
Gross proceed from convertible preferred stock
Gross Proceeds From Issuance Of Convertible Preferred Stock
Number of shares converted into shares
Conversion Of Stock Shares Convertible
Sale of preferred stock, net of issuance costs, Shares
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs
Conversion of preferred stock, Shares
Number of shares converted into shares
Estimated fair value of preferred stock purchase right liability
Change in fair value of purchase right liability
Stock public offering price
Sale Of Stock Price Per Share
Cash dividends declared or paid
Dividends Cash
Common stock number of voting rights for each share.
Common stock, voting rights
Common Stock Voting Rights
Common stock entitled, number of vote for each share
Common Stock Number Of Voting Rights For Each Share
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Two thousand fifteen equity incentive plan.
2015 Plan
Two Thousand Fifteen Equity Incentive Plan [Member]
Two thousand twenty performance incentive plan.
2020 Plan
Two Thousand Twenty Performance Incentive Plan [Member]
2020 Employee Stock Purchase Plan
Employee Stock [Member]
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Restricted Stock Options
Restricted Stock [Member]
Separation and release agreement.
Separation and Release Agreement
Separation And Release Agreement [Member]
Title of Individual
Title Of Individual [Axis]
Title of Individual
Title Of Individual With Relationship To Entity [Domain]
Matthew Plunkett
Chief Financial Officer [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares issued
Share Based Compensation Arrangement By Share Based Payment Award Shares Issued In Period
Increase in share limit as percentage of outstanding shares of common stock on last trading day in prior year.
Number of common stock authorized for issuance
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized
Increase in share limit as percentage of outstanding shares of common stock on last trading day in prior year
Increase In Share Limit As Percentage Of Outstanding Shares Of Common Stock On Last Trading Day In Prior Year
Number of awards granted
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
Number of common stock available for issuance
Common Stock Capital Shares Reserved For Future Issuance
Two thousand twenty performance incentive and two thousand fifteen equity incentive plan.
2020 Plan and 2015 Plan
Two Thousand Twenty Performance Incentive And Two Thousand Fifteen Equity Incentive Plan [Member]
Number of shares, outstanding beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Number of shares, granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Number of shares, exercised
Number of shares, forfeited
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Number of shares, outstanding ending balance
Number of shares, exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Number of shares, vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
Weighted-average exercise price, outstanding beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Weighted-average exercise price, granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Weighted-average exercise price, exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Weighted-average exercise price, forfeited
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Weighted-average exercise price, outstanding ending balance
Weighted-average exercise price, exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Weighted-average exercise price, vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
Weighted-average remaining contractual term (in years), outstanding balance
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Weighted-average remaining contractual term (in years), exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Weighted-average remaining contractual term (in years), vested and expected to vest
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
Aggregate intrinsic value, outstanding balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Aggregate intrinsic value, exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Aggregate intrinsic value, vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Aggregate Intrinsic Value
Weighted-average grant-date fair value of stock option grants per share
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Intrinsic value of options exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Fair value of options vested
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
Share based compensation arrangement by share based payment award offering period.
Maximum percentage of employee compensation eligible for plan
Share Based Compensation Arrangement By Share Based Payment Award Maximum Employee Subscription Rate
Offering period
Share Based Compensation Arrangement By Share Based Payment Award Offering Period
Commons stock purchase price as percentage of fair value
Sharebased Compensation Arrangement By Sharebased Payment Award Purchase Price Of Common Stock Percent
Shares subject to repurchase
Stock Repurchase Program Number Of Shares Authorized To Be Repurchased
Other long-term liabilities
Common Stock Options Granted and Outstanding
Employee Stock Option [Member]
Reserved for Future Equity Award Grants
Reserved for Future ESPP Issuances
Common stock reserved for future issuance
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Research and Development
Research And Development Expense [Member]
General and Administrative
General And Administrative Expense [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Share-based compensation expense
Allocated Share Based Compensation Expense
Unrecognized compensation cost
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Unrecognized compensation cost, expected to be recognized over weighted average remaining service period
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Agreement execution date.
Period within severance benefits payable after termination date.
Share-based compensation
Severance benefits expense
Severance Costs1
Agreement execution date
Agreement Execution Date
Period in which severance benefits payable after termination date
Period Within Severance Benefits Payable After Termination Date
Share based compensation arrangement by share based payment award fair value assumptions common stock fair value.
Common stock fair value
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Common Stock Fair Value
Risk-free interest rate, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
Risk-free interest rate, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
Expected volatility, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
Expected volatility, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
Expected term (in years)
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Expected dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Dividends issued for options
Dividends Share Based Compensation
Dividends expected to be issued over life of options
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Payments
Estimated dividend yield
Income taxes.
Income taxes.
Income Taxes [Table]
Income Taxes [Table]
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
Federal
Domestic Country [Member]
California State
State And Local Jurisdiction [Member]
Tax Period
Tax Period [Axis]
Tax Period
Tax Period [Domain]
Expiration year one.
2035
Expiration Year One [Member]
Expiration year two.
2036
Expiration Year Two [Member]
Carry forward indefinitely.
Carry Forward Indefinitely
Carry Forward Indefinitely [Member]
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Tax Credit Carryforward, Name
Tax Credit Carryforward Name [Domain]
Research and Development Credit Carry Forwards
Research [Member]
Net operating loss and tax credit carryforwards to offset.
Net Operating Loss and Tax Credit Carryforwards to Offset
Net Operating Loss And Tax Credit Carryforwards To Offset [Member]
Income Taxes [Line Items]
Income Taxes [Line Items]
Provision or benefit for income taxes
Income Tax Expense Benefit
Income tax reconciliation permanent items.
Income tax reconciliation change in fair value of derivative liability.
Income tax benefit at statutory rates
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
State income tax, net of federal benefit
Income Tax Reconciliation State And Local Income Taxes
Permanent items
Income Tax Reconciliation Permanent Items
Research and development credits
Income Tax Reconciliation Tax Credits Research
Other
Income Tax Reconciliation Other Adjustments
Change in valuation allowance
Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
Change in fair value of derivative liabilities
Income Tax Reconciliation Change In Fair Value Of Derivative Liability
Income tax expense
Deferred tax assets depreciation and amortization.
Deferred tax assets lease liability.
Deferred tax liabilities right of use asset.
Deferred tax liabilities depreciation and amortization.
Deferred tax assets:
Components Of Deferred Tax Assets [Abstract]
Net operating loss carry forwards
Deferred Tax Assets Operating Loss Carryforwards
Depreciation and amortization
Deferred Tax Assets Depreciation And Amortization
Research and development credits
Deferred Tax Assets Tax Credit Carryforwards Research
Accrued expenses
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
Lease liability
Deferred Tax Assets Lease Liability
Other, net
Deferred Tax Assets Other
Total deferred tax assets
Deferred Tax Assets Gross
Valuation allowance for deferred tax assets
Deferred Tax Assets Valuation Allowance
Deferred tax assets, net of valuation allowance
Deferred Tax Assets Net
Deferred tax liabilities:
Deferred Tax Liabilities Net [Abstract]
Right-of-use asset
Deferred Tax Liabilities Right Of Use Asset
Depreciation and amortization
Deferred Tax Liabilities Depreciation And Amortization
Net deferred tax assets
Deferred Tax Assets Liabilities Net
Increase in valuation allowance of net deferred tax assets
Valuation Allowance Deferred Tax Asset Change In Amount
Net deferred tax asset
Operating loss carryforwards, expiration year.
Net operating loss carryforwards
Operating Loss Carryforwards
Net operating loss carryforwards, expire
Operating Loss Carryforwards Expiration Year
Tax credit carryforward expiration year.
Tax credit carryforwards
Tax Credit Carryforward Amount
Tax credit carryforwards, expire
Tax Credit Carryforward Expiration Year
Changes in ownership by stockholders holding percentage.
Changes in ownership by stockholders holding percentage
Changes In Ownership By Stockholders Holding Percentage
Gross unrecognized tax benefits
Unrecognized Tax Benefits
Unrecognized tax benefits, penalties and interest expense
Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
Balance at the beginning of the year
Additions for tax positions taken in prior years
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
Additions for tax positions taken in current year
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
Balance at the end of the year