Entity Address, City or Town
Entity Address, City or Town
Deferred tax liabilities:
Deferred Tax Liabilities, Net [Abstract]
Reconciliation on Income Taxes Amount Computed by Applying Statutory Federal Income Tax Rate to Net Loss
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Entity Ex Transition Period
Entity Ex Transition Period
Fair Value Disclosures [Abstract]
Earnings Per Share [Abstract]
Increase in share limit as percentage of outstanding shares of common stock on last trading day in prior year
Increase In Share Limit As Percentage Of Outstanding Shares Of Common Stock On Last Trading Day In Prior Year
Increase in share limit as percentage of outstanding shares of common stock on last trading day in prior year.
Quoted Prices in Active Markets for Identical Assets (Level 1)
Fair Value, Inputs, Level 1 [Member]
Number of non-exclusive rights to gene editing targets licenses received
Number Of Non Exclusive Rights To Gene Editing Targets licenses received
Number of non exclusive rights to gene editing targets licenses received.
Federal
Domestic Tax Authority [Member]
Issuance of common stock upon secondary offering, net of issuance costs
Stock Issued During Period, Value, New Issues
Research and Development Costs
Research and Development Expense, Policy [Policy Text Block]
Cash flows from financing activities:
Net Cash Provided by (Used in) Financing Activities [Abstract]
Estimated dividend yield
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Weighted-average remaining contractual term (in years), outstanding ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock
Fair Value Measurement With Unobservable Inputs Reconciliations Reclassification Of Preferred Stock Purchase Right Liability To Equity Upon Issuance Of Convertible Preferred Stock
Fair value measurement with unobservable inputs reconciliations Reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock.
Amendment Flag
Amendment Flag
Number of common stock authorized for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Subsequent Event Type
Subsequent Event Type [Domain]
Right-of-use assets obtained in exchange for operating lease liabilities resulting from new leases
Right-of-use Assets Obtained in Exchange for Operating Lease Liabilities Resulting from New Leases
Right-of-use assets obtained in exchange for operating lease liabilities resulting from new leases.
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Right-of-use assets
Receivable under research cost sharing provision.
Receivable Under Research Cost Sharing Provision
Receivable under research cost sharing provision
Lease liabilities arising from obtaining right-of-use assets
Lease Liabilities Arising From Obtaining Right Of Use Assets [Abstract]
Lease liabilities arising from obtaining right-of-use assets
Depreciation and amortization
Deferred Tax Assets Depreciation And Amortization
Deferred tax assets depreciation and amortization.
Cash paid for amounts included in the measurement of lease liabilities
Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract]
Cash paid for amounts included in the measurement of lease liabilities.
Less imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Net Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Summary of Additional Information Related to Stock Options
Schedule Of Share Based Compensation Additional Information Related To Stock Options
Schedule of share based compensation additional information related to stock options.
Cash and Cash Equivalents
Cash and Cash Equivalents [Domain]
Less: weighted average unvested common stock issued upon early exercise of common stock options
Weighted Average Number Of Shares Unvested Common Stock Issued Upon Early Exercise Of Common Stock Options
Weighted average number of shares unvested common stock issued upon early exercise of common stock options.
Statement [Table]
Statement [Table]
Non-current
Operating lease liabilities, net of current portion
Operating Lease, Liability, Noncurrent
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Operating cash flows used for operating leases
Operating Lease, Payments
MaxCyte license agreement.
MaxCyte License Agreement [Member]
MaxCyte License Agreement
Issuance of common stock upon employee stock purchase plan,share
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Number of operating segments
Number of Operating Segments
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Number of common stock available for issuance
Common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Auditor Firm ID
Weighted-average grant date fair value per share, outstanding ending balance
Weighted-average grant date fair value per share, outstanding beginning balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value per share, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Initial Lease Agreement and Additional Lease Agreement
Initial Lease Agreement And Additional Lease Agreement [Member]
Initial Lease Agreement And Additional Lease Agreement.
Income Tax Authority
Income Tax Authority [Domain]
Additional number of days to replace letter of credit
Additional number of days to replace letter of credit.
Amounts owed under agreement.
Amounts Owed Under Agreement
Amounts owed under the agreement
Accounting Standards Update 2019-12 [Member]
ASU 2019-12
Product and Service
Product and Service [Axis]
Reserved for Future ESPP Issuances
2020 Employee Stock Purchase Plan
Employee Stock [Member]
Accrued compensation
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
Leases
Lessee, Operating Leases [Text Block]
Options
Share-Based Payment Arrangement, Option [Member]
Weighted-average remaining lease term
Operating Lease, Weighted Average Remaining Lease Term
Liabilities and Equity
Total liabilities and stockholders' equity
Tax Period
Tax Period [Axis]
Plan Name
Plan Name [Domain]
Temporary equity, issuance of Series B convertible preferred stock upon conversion of promissory notes
Temporary Equity Stock Issued During Period Value Upon Conversion Of Promissory Notes
Temporary equity stock issued during period value upon conversion of promissory notes.
Denominator:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Corporate Office and Laboratory Facilities
Corporate Office And Laboratory Facilities [Member]
Corporate office and laboratory facilities.
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Description of the reverse stock split
Stockholders' Equity, Reverse Stock Split
Description of Business
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Aggregate cash proceeds
Proceeds from ESPP purchases
Proceeds from Stock Plans
Net Operating Loss and Tax Credit Carryforwards to Offset
Net Operating Loss And Tax Credit Carryforwards To Offset [Member]
Net operating loss and tax credit carryforwards to offset.
Change in fair value of derivative liabilities
Income Tax Reconciliation Change In Fair Value Of Derivative Liability
Income tax reconciliation change in fair value of derivative liability.
Sale of Stock
Sale of Stock [Domain]
Total current liabilities
Liabilities, Current
Realized loss on investments
Debt Securities, Available-for-Sale, Realized Loss
Issuance of common stock upon employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Net operating loss carryforwards
Operating Loss Carryforwards
Operating Loss Carryforwards, Total
2025
Lessee, Operating Lease, Liability, to be Paid, Year Three
Proceeds from ATM offering, net of issuance costs
Proceeds From At The Market Offering Net of Issuance Costs
Proceeds from at the market offering net of issuance costs.
Short-term lease expense
Short-Term Lease, Cost
Cash, cash equivalents restricted cash and short-term investments
Cash Cash Equivalents Restricted Cash And Short Term Investments
Cash cash equivalents restricted cash and short term investments.
Income Taxes
Income Tax, Policy [Policy Text Block]
Percentage of sublicensing income
Percentage Of Sublicensing Income
Percentage of sublicensing income.
Maximum percentage of employee compensation eligible for plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Series B Convertible Preferred Stock
Series B Convertible Preferred Stock [Member]
Series B convertible preferred stock.
Matthew Plunkett
Chief Financial Officer [Member]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Research Equipment
Research Equipment [Member]
Research equipment.
Proceeds from Issuance or Sale of Equity, Total
Proceeds from Issuance or Sale of Equity
Issuance and sale of equity
Entity Small Business
Entity Small Business
Total cash, cash equivalents and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Investments
Investments [Domain]
Total current assets
Assets, Current
Property Plant And Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Weighted-average number of common shares used in net loss per share, basic
Weighted average shares used to compute net loss per share, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
City Area Code
City Area Code
Aggregate intrinsic value, outstanding balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Interest expense
Non Cash Interest Expense On Convertible Notes
Non-cash interest expense on convertible notes.
Number of shares, forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Schedule of Prepaid Expenses and Other Current Assets
Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block]
Schedule of prepaid expenses and other current assets.
Share-Based Payment Arrangement [Abstract]
Total liabilities
Liabilities
Secondary Offering
Private Placement [Member]
Document Period End Date
Document Period End Date
Lease Contractual Term [Domain]
Restricted Stock Options
Restricted Stock [Member]
Unrecognized tax benefits increases (decreases) resulting from prior period tax positions.
Unrecognized Tax Benefits Increases Decreases Resulting From Prior Period Tax Positions
Increases (decreases) related to tax positions taken in prior years
Construction in Progress
Construction in Progress [Member]
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Share-based compensation
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Letter of credit notice period by financial institution before annual expiration date
Letter Of Credit Notice Period By Financial Institution Before Annual Expiration Date
Letter of credit notice period by financial institution before annual expiration date.
Weighted-average grant-date fair value of stock option grants per share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Renewal term
Lessee, Operating Lease, Renewal Term
Available for sale securities, Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Vivarium
Vivarium [Member]
Vivarium.
Statistical Measurement
Statistical Measurement [Axis]
GSK
Glaxo Smith Kline Intellectual Property Development Limited And Glaxo Group Limited [Member]
GlaxoSmithKline Intellectual Property Development Limited and Glaxo Group Limited.
Other current assets
Other Assets, Current
Fair value of preferred stock purchase right liability percentage
Fair Value Of Preferred Stock Purchase Right Liability Percentage
Fair value of preferred stock purchase right liability percentage.
Subsequent Event [Line Items]
Total assets
Assets
Depreciation and amortization
Deferred Tax Liabilities Depreciation And Amortization
Deferred tax liabilities depreciation and amortization.
Conversion of convertible preferred stock to common stock
Conversion of convertible preferred stock to common stock, Shares
Stock Issued During Period, Shares, Conversion of Convertible Securities
California State
State and Local Jurisdiction [Member]
Net loss per share, diluted
Net loss per share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Retirement Plan Type
Retirement Plan Type [Axis]
Summarizes the Outstanding Potentially Dilutive Securities Excluded in Calculation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
401 (K) Plan
K Plan [Member]
401 (K) Plan.
Estimated fair value of preferred stock purchase right liability
Balance, December 31, 2020
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Balance, January 1, 2020
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Document Fiscal Period Focus
Document Fiscal Period Focus
Restricted cash
Restricted Cash
Restricted Cash, Total
Preferred Stock Purchase Right Liability
Preferred Stock Purchase Right Liability Policy [Text Block]
Preferred stock purchase right liability.
Carry Forward Indefinitely
Carry Forward Indefinitely [Member]
Carry forward indefinitely.
Deferred offering costs
Deferred Offering Costs
Valuation allowance for deferred tax assets
Deferred Tax Assets, Valuation Allowance
Deferred Tax Assets, Valuation Allowance, Total
Temporary equity, conversion of convertible preferred stock to common stock, Shares
Conversion of Stock, Shares Converted
Preferred stock, $0.0001 par value; 54,350,179 shares authorized at December 31, 2022; no shares issued and outstanding at December 31, 2022 and 2021
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
License Agreement
License Agreement [Member]
License agreement.
Share-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Lease expiration month and year
Lease Expiration Month And Year
Lease expiration month and year.
Counterparty Name
Counterparty Name [Domain]
Total operating lease liabilities
Total lease liability
Operating Lease, Liability
Lease liabilities
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
Temporary equity, reacquisition of beneficial conversion feature upon settlement of promissory notes
Temporary Equity Reacquisition Of Beneficial Conversion Feature Upon Settlement Of Promissory Notes
Temporary equity, reacquisition of beneficial conversion feature upon settlement of promissory notes.
Short-Term Debt, Type [Axis]
Collaboration and License Agreement
Collaboration And License Agreement [Member]
Collaboration and license agreement.
Statement of Financial Position [Abstract]
Temporary equity, shares issued
Convertible preferred stock, shares issued
Temporary Equity, Shares Issued
Change in fair value of preferred stock purchase right liability
Change in fair value of preferred stock purchase right liability
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings
Entity File Number
Securities Act File Number
Scenario
Scenario [Domain]
Statement of Cash Flows [Abstract]
Balance Sheet Related Disclosures [Abstract]
2028 and thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Second Amendment Of Additional Lease Agreement
Second Amendment Of Additional Lease Agreement [Member]
Second amendment of additional lease agreement.
Tax credit carryforwards, expire
Tax Credit Carryforward Expiration Year
Tax credit carryforward expiration year.
Expected Base Rent Over Lease Term
Expects to pay base rent over the lease term
Expected base rent over the lease term.
Statistical Measurement
Statistical Measurement [Domain]
Statement of Stockholders' Equity [Abstract]
Sale of Stock
Sale of Stock [Axis]
Commons stock purchase price as percentage of fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Net operating loss carryforwards, expire
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards, expiration year.
Comprehensive loss:
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Auditor Location
Class of Stock
Class of Stock [Domain]
Liability regard to loss contingencies
Loss Contingency Accrual
Loss Contingency Accrual, Beginning Balance
Loss Contingency Accrual, Ending Balance
Revenue Recognition
Revenue from Contract with Customer [Policy Text Block]
Components of Lease Expense
Lease, Cost [Table Text Block]
Milestone payment
Milestone Payment Upon Completion Of Regulatory Milestone Related To Clinical Development
Milestone payment upon completion of regulatory milestone related to the clinical development.
Summary of Fair Value of Financial Instrument
Fair Value, by Balance Sheet Grouping [Table Text Block]
Subsequent Events [Abstract]
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Schedule of Supplemental Information related to Operating Leases
Schedule Of Supplemental Information Related To Operating Leases Table [Text Block]
Schedule of supplemental information related to operating leases.
Other comprehensive loss:
Other comprehensive loss:
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Weighted-average remaining contractual term (in years), exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Potential milestone payments
Potential Milestone Payments
Potential milestone payments.
Proceeds from stock option exercises
Proceeds from Stock Options Exercised
Net proceeds from offering
Net proceeds from public offering
Proceeds from Issuance of Common Stock
Temporary equity, Issuance of Series B convertible preferred stock, net of issuance costs
Temporary Equity, Stock Issued During Period, Value, New Issues
Research and development credits
Deferred Tax Assets, Tax Credit Carryforwards, Research
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Accounting policies.
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Separation and Release Agreement
Separation And Release Agreement [Member]
Separation and release agreement.
Concentration of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Antidilutive Securities
Antidilutive Securities [Axis]
Lease expiration year
Lease Expiration Year
Lease expiration year.
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Preferred stock, par value
Preferred Stock, Par or Stated Value Per Share
Corporate Office and Laboratory Space
Corporate Office And Laboratory Space [Member]
Corporate office and laboratory space.
Available for sale securities, Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Lessee Lease Description [Line Items]
Lessee, Lease, Description [Line Items]
Balance Sheet Components
Supplemental Balance Sheet Disclosures [Text Block]
Subsequent Events
Subsequent Events [Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Weighted-average number of common shares used in net loss per share, diluted
Weighted average shares used to compute net loss per share, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Employee stock purchase plan look-back period
Employee stock purchase plan look-back period.
State income tax, net of federal benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
Corporate Debt Securities
Corporate Debt Securities [Member]
General and Administrative
General and Administrative Expense [Member]
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Commercial Paper
Commercial Paper [Member]
Current Fiscal Year End Date
Current Fiscal Year End Date
Investment Type
Investment Type [Axis]
Financial Instruments
Financial Instruments [Domain]
Accounting Policies [Table]
Accounting Policies [Table]
Accounting policies.
Cash, cash equivalents and restricted cash at beginning of year
Cash, cash equivalents and restricted cash at end of year
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Preferred stock purchase right liability
Preferred Stock Purchase Right Liability Fair Value Disclosure
Preferred stock purchase right liability fair value disclosure.
Other long-term assets
Other Assets, Noncurrent
Other Assets, Noncurrent, Total
Entity Address, Address Line One
Entity Address, Address Line One
Accrued interest receivable
Interest Receivable, Current
Document Annual Report
Document Annual Report
Supplemental disclosures of non-cash investing and financing activities:
Supplemental Cash Flow Information [Abstract]
2036
Expiration Year Two [Member]
Expiration year two.
Deferred tax assets:
Components of Deferred Tax Assets [Abstract]
Common stock fair value
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Common Stock Fair Value
Share based compensation arrangement by share based payment award fair value assumptions common stock fair value.
Fair value of preferred stock purchase right liability outstanding term
Fair Value Of Preferred Stock Purchase Right Liability Outstanding Term
Fair value of preferred stock purchase right liability outstanding term.
Restricted cash
Restricted Cash, Noncurrent
Income Taxes [Line Items]
Income Taxes [Line Items]
Income taxes.
Provision or benefit for income taxes
Income tax expense
Income Tax Expense (Benefit)
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Income Taxes
Income Tax Disclosure [Text Block]
Right-of-use asset
Deferred Tax Liabilities Right Of Use Asset
Deferred tax liabilities right of use asset.
Preferred stock, shares issued
Preferred Stock, Shares Issued
Preferred Stock, Shares Issued, Total
Balance Sheet Location [Domain]
Purchase of property and equipment
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Income Tax Disclosure [Abstract]
Temporary equity, beneficial conversion feature upon issuance of convertible
Temporary Equity Beneficial Conversion Feature Upon Issuance Of Convertible
Temporary equity beneficial conversion feature upon issuance of convertible.
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Common Stock Options And Restricted Stock Units Granted And Outstanding
Common Stock Options And Restricted Stock Units [Member]
Common stock options and restricted stock units.
Reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock
Temporary Equity Reclassification Of Preferred Stock Purchase Right Liability To Equity Upon Issuance Of Convertible Preferred Stock
Temporary equity reclassification of preferred stock purchase right liability to equity upon issuance of convertible preferred stock.
Common stock shares issued and sold
Issuance of common stock upon secondary offering, net of issuance costs, Shares
Stock Issued During Period, Shares, New Issues
Changes in ownership by stockholders holding percentage
Changes In Ownership By Stockholders Holding Percentage
Changes in ownership by stockholders holding percentage.
Temporary equity, issuance of Series B convertible preferred stock upon conversion of promissory notes, Shares
Temporary Equity Stock Issued During Period Shares Upon Conversion Of Promissory Notes
Temporary equity stock issued during period shares upon conversion of promissory notes.
Assets:
Assets, Fair Value Disclosure [Abstract]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Share-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Temporary equity, conversion of convertible preferred stock to common stock
Conversion of Stock, Amount Converted
Auditor Name
Equity [Abstract]
Weighted-average exercise price, forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Loss from operations
Operating Income (Loss)
Shares issued
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Lessee option to extend description
Lessee, Operating Lease, Option to Extend
Weighted average common shares outstanding
Weighted Average Number of Shares Issued, Basic
Amount held as collateral for letters of credit issued to landlord
Amount held as collateral for letters of credit issued to landlord.
Additional paid-in capital
Additional Paid in Capital, Common Stock
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Payments made under collaborative arrangement.
Payments Made Under Collaborative Arrangement
Amount paid under the agreement
Scenario
Scenario [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Entity Filer Category
Entity Filer Category
Money market funds
Money Market Funds, at Carrying Value
2035
Expiration Year One [Member]
Expiration year one.
Total operating expenses
Operating Expenses
Entity Current Reporting Status
Entity Current Reporting Status
ICFR Auditor Attestation Flag
Schedule of Accrued Other Current Liabilities
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Aggregate intrinsic value, exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Reserved for Future Equity Award Grants
2020 Plan
Two Thousand Twenty Performance Incentive Plan [Member]
Two thousand twenty performance incentive plan.
Investments sold
Debt Securities, Available-for-Sale, Sold at Par Value
Short-term investments, available-for-sale
Debt Securities, Available-for-Sale, Current
Debt Securities, Available-for-sale, Current, Total
Fair value of preferred stock purchase right liability discount rate
Fair Value Of Preferred Stock Purchase Right Liability Discount Rate
Fair value of preferred stock purchase right liability discount rate.
Dividends issued for options
Dividend, Share-Based Payment Arrangement
Dividend, Share-based Payment Arrangement, Total
Stockholders' Equity
Stockholders' Equity Note Disclosure [Text Block]
Beginning Balance
Ending Balance
Stockholders' Equity Attributable to Parent
Total stockholders' equity
Interest income
Investment Income, Net
Investment Income, Net, Total
Realized loss on investments
Realized gain or loss on available-for-sale securities
Debt Securities, Available-for-Sale, Realized Gain (Loss)
Debt Securities, Available-for-sale, Realized Gain (Loss), Total
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss)
Short-term investments
Short-Term Investments [Member]
Commitments
Commitments and Contingencies, Policy [Policy Text Block]
Acquisitions of property and equipment
Noncash or Part Noncash Acquisition, Fixed Assets Acquired
Available-for-sale securities, Maturity (in years)
Debt Securities, Available-for-Sale, Term
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location
Income Statement Location [Axis]
Number of shares, forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Common stock, $0.0001 par value; 100,000,000 shares authorized at December 31, 2022; 48,877,806 and 32,971,107 shares issued and outstanding at December 31, 2022 and 2021, respectively
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract]
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Equity Components
Equity Components [Axis]
Common Stock Options
Common Stock Options [Member]
Common stock options.
Accounting Standards Update
Accounting Standards Update [Domain]
ASU 2016-13
Accounting Standards Update 2016-13 [Member]
Payments of deferred offering costs.
Payments of Deferred Offering Costs
Payments of deferred offering costs
Prepaid expenses
Prepaid Expense, Current
Prepaid Expense, Current, Total
Leases [Abstract]
Entity Emerging Growth Company
Entity Emerging Growth Company
Operating expenses:
Operating Expenses [Abstract]
Lease liability
Deferred Tax Assets Lease Liability
Deferred tax assets lease liability.
Proceeds from maturities of available-for-sale securities
Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-Sale
Retirement Plan Type
Retirement Plan Type [Domain]
License agreement term
License Agreement Term
License agreement term.
Schedule Of Stock By Class [Table]
Schedule of Stock by Class [Table]
Letter of Credit [Member]
Letter of Credit
Reduction of research and development expense resulting from partial reimbursement
Reduction Of Research And Development Expense Resulting From Partial Reimbursement
Reduction of research and development expense resulting from partial reimbursement.
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
2015 Plan
Two Thousand Fifteen Equity Incentive Plan [Member]
Two thousand fifteen equity incentive plan.
Entity Voluntary Filers
Entity Voluntary Filers
Expected volatility, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Research and Development Credit Carry Forwards
Research Tax Credit Carryforward [Member]
Retirement Benefits [Abstract]
Depreciation and amortization expense
Depreciation, Depletion and Amortization, Nonproduction
Depreciation, Depletion and Amortization, Nonproduction, Total
Document Transition Report
Document Transition Report
Maximum monthly base rent after increase on annual basis.
Maximum Monthly Base Rent After Increase on Annual Basis
Maximum monthly base rent after increase on annual basis
Total
Assets, Fair Value Disclosure
Weighted-average grant date fair value per share, granted
Weighted-average grant date fair value for the ESPP
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Total other income (expense), net
Nonoperating Income (Expense)
Reverse Stock Split
Reverse Stock Split Policy Policy [Text Block]
Reverse stock split policy.
Depreciation and amortization expense
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Impairment losses on long-lived assets
Impairment, Long-Lived Asset, Held-for-Use
Impairment, Long-Lived Asset, Held-for-Use, Total
Initial lease agreement.
Initial Lease Agreement [Member]
Initial Lease Agreement
Percentage of licensors royalties
Percentage Of Licensors Royalties
Percentage of Licensors royalties.
Stock public offering price
Sale of Stock, Price Per Share
Collaborative Arrangement Disclosure [Text Block]
Collaboration and License Agreements
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Weighted-average exercise price, exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Tax Period
Tax Period [Domain]
NUS and St. Jude
National University Of Singapore And St Jude Children S Research Hospital [Member]
National University of Singapore and St. Jude Children's Research Hospital.
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Other accrued and current liabilities
Accounts Payable and Other Accrued Liabilities, Current
Vesting of shares of common stock subject to repurchase
Stock Issued During Period Value Vesting Of Shares Of Common Stock Subject To Repurchase
Stock issued during period value vesting of shares of common stock subject to repurchase.
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Convertible Preferred Stock
Temporary Equity Policy [Text Block]
Temporary equity.
Current
Operating lease liabilities, current portion
Operating Lease, Liability, Current
Defined contribution plan, description
Defined Contribution Plan, Description
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Net operating loss carry forwards
Deferred Tax Assets, Operating Loss Carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Entity Registrant Name
Entity Registrant Name
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Shares subject to repurchase
Stock Repurchase Program, Number of Shares Authorized to be Repurchased
Net Loss Per Share
Earnings Per Share [Text Block]
Schedule of Fair Value of Stock Options Estimated on Date of Grant Using Black-Scholes Option Pricing Model
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Class of Stock
Class of Stock [Axis]
U.S. Government Securities
US Government Agencies Debt Securities [Member]
Lessee Lease Description [Table]
Lessee, Lease, Description [Table]
Share-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Share-based Payment Arrangement, Noncash Expense, Total
Total property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Weighted-average remaining contractual term (in years), vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Award Type
Award Type [Domain]
Statement [Line Items]
Statement [Line Items]
Liabilities:
Liabilities, Fair Value Disclosure [Abstract]
Weighted-average exercise price, vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Title of 12(b) Security
Title of 12(b) Security
Additional tenant improvement allowances
Additional Tenant Improvement Allowances
Additional tenant improvement allowances.
Common Stock
Common Stock [Member]
Contractual term of options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Cash flows from operating activities:
Net Cash Provided by (Used in) Operating Activities [Abstract]
Equity Component
Equity Component [Domain]
Fair Value of Financial Instruments
Fair Value Measurement, Policy [Policy Text Block]
Number of days to replace each letter of credit
Number of days to replace each letter of credit.
Purchases of available-for-sale securities
Payments to Acquire Debt Securities, Available-for-Sale
Convertible Preferred Stock
Convertible Preferred Stock [Member]
Product revenue
Collaboration revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Entity Address, State or Province
Entity Address, State or Province
2026
Lessee, Operating Lease, Liability, to be Paid, Year Four
Net decrease in cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Document Type
Document Type
Research and development credits
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
U.S. Government Securities
US Government Corporations and Agencies Securities [Member]
Entity Shell Company
Entity Shell Company
Share-based compensation
Share-based compensation expense
Share-Based Payment Arrangement, Expense
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Accrued expenses
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Section 174 Capitalized R&D
Deferred Tax Assets section one seventy four Capitalized Research and development
Deferred tax assets Section 174 capitalized R&D.
Security Exchange Name
Security Exchange Name
NK cell products.
NK Cell Products [Member]
NK Cell Products
Class Of Stock [Line Items]
Class of Stock [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Basis of Presentation and Significant Accounting Policies
Significant Accounting Policies [Text Block]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Acquisitions of property and equipment in accounts payable
Noncash Or Part Noncash Acquisition Fixed Assets Acquired Included In Accounts Payable
Noncash or part noncash acquisition fixed assets acquired included in accounts payable.
Unrecognized compensation cost, expected to be recognized over weighted average remaining service period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Weighted-average remaining contractual term (in years), outstanding balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Collaboration agreement.
Collaboration Agreement [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Operating lease expense
Operating Lease, Cost
Restricted Stock Unit Activity
Restricted Stock Units
Restricted Stock Units (RSUs) [Member]
Permanent items
Income Tax Reconciliation Permanent Items
Income tax reconciliation permanent items.
Schedule of Maturities of Operating Lease Liabilities
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Summary of Changes in Gross Unrecognized Tax Benefits
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
2020 Plan and 2015 Plan
Two Thousand Twenty Performance Incentive And Two Thousand Fifteen Equity Incentive Plan [Member]
Two thousand twenty performance incentive and two thousand fifteen equity incentive plan.
Summary of Restricted Stock Unit Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Recent Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Accretion of discount and amortization of premium on investments, net
Accretion (Amortization) of Discounts and Premiums, Investments
Underwriters Option to Purchase Additional Shares
Over-Allotment Option [Member]
Operating Leases, Future Minimum Payments Receivable, Current
Operating lease receivable
Significant Other Observable Inputs (Level 2)
Fair Value, Inputs, Level 2 [Member]
Available for sale securities,Estimated Fair Value
Debt Securities, Available-for-Sale
Debt Securities, Available-for-sale, Total
Cash flows from investing activities:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Computers and Software
Computers And Software [Member]
Computers and software.
Vesting of shares of common stock subject to repurchase, Shares
Stock Issued During Period Shares Vesting Of Shares Of Common Stock Subject To Repurchase
Stock issued during period shares vesting of shares of common stock subject to repurchase.
Additions for tax positions taken in current year
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Increases related to tax positions taken in current year
Commitments and contingencies (Note 7)
Commitments and Contingencies
Shares issued during period
Common stock, shares issued
Common Stock, Shares, Issued
Common Stock, Shares, Issued, Total
Net sales milestone payments.
Net Sales Milestone Payments
Net sales milestone payments
Annual license maintenance fee
Annual License Maintenance Fee
Annual license maintenance fee.
Minimum
Minimum [Member]
Less tenant improvement receivable
Tenant improvement receivable
Tenant improvement receivable.
Offering period
Share Based Compensation Arrangement By Share Based Payment Award Offering Period
Share based compensation arrangement by share based payment award offering period.
Operating lease liabilities:
Operating Lease, Liability [Abstract]
Risk-free interest rate, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Leases
Lessee, Leases [Policy Text Block]
Weighted-average exercise price, exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Accounting Standards Update
Accounting Standards Update [Axis]
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Accrued and other current liabilities
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Lease commencement date.
Lease Commencement Date
LeaseCommencementDate
Lease commencement date
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders' equity:
Counterparty Name
Counterparty Name [Axis]
Entity Address, Address Line Two
Entity Address, Address Line Two
Cash and Cash Equivalents
Cash and Cash Equivalents [Axis]
Weighted-average grant date fair value per share, forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Award Type
Award Type [Axis]
Others
Other Noncash Income (Expense)
Other Noncash Income (Expense), Total
Subsequent Event
Subsequent Event [Member]
Unrecognized compensation cost
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Total deferred tax assets
Deferred Tax Assets, Gross
Loss Contingencies [Table]
Loss Contingencies [Table]
Impairment of Long-Lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Intrinsic value of options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Other income (expense), net
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other expense, net
Potential future payments based on achievement of milestones.
Potential Future Payments Based On Achievement Of Milestones
Potential future payments
Other income (expense), net:
Nonoperating Income (Expense) [Abstract]
Research and development costs
Research and development
Research and Development Expense
Research and Development Expense, Total
Total undiscounted future minimum lease payments
Lessee, Operating Lease, Liability, to be Paid
Upfront payment
License Agreement Upfront Payment
License agreement upfront payment.
Lessee, Operating Lease, Term of Contract
Lessee, operating lease, term of contract
Dividends expected to be issued over life of options
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments
Monthly base rent.
Monthly Base Rent
Monthly base rent
Entity Central Index Key
Entity Central Index Key
Increase in valuation allowance of net deferred tax assets
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Liabilities recorded for agreements
Guarantor Obligations, Current Carrying Value
Total short-term investments
Short-Term Investments
Short-term Investments, Total
Numerator:
Net Income (Loss) Attributable to Parent [Abstract]
Accounting Policies [Abstract]
Less accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Schedule Of Property Plant And Equipment [Table]
Property, Plant and Equipment [Table]
Development and regulatory approval milestones.
Development and Regulatory Approval Milestones [Member]
Development and Regulatory Approval Milestones
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Commercial paper
Commercial Paper, at Carrying Value
Share-Based Compensation
Share-Based Payment Arrangement [Text Block]
Cash received for tenant improvement allowances to be repaid.
Cash Received for Tenant Improvement Allowances to be Repaid
Cash received for tenant improvement allowances to be repaid
Research collaboration agreement.
Research Collaboration Agreement [Member]
Research Collaboration Agreement
Subsequent Event [Table]
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Weighted-average exercise price, outstanding beginning balance
Weighted-average exercise price, outstanding ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Research and Development
Research and Development Expense [Member]
Risk-free interest rate, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Upfront payment, shares issued
Stock Issued During Period Shares Issued Upfront Payments
Stock issued during period shares issued upfront payments.
Total lease expense
Lease, Cost
Right-of-use assets obtained in exchange for operating lease liabilities
Operating leases
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Employer contribution, percent
Defined Contribution Plan, Employer Matching Contribution, Percent of Employees' Gross Pay
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Accumulated Deficit
Retained Earnings [Member]
Security Deposit
Security deposit
Tax Credit Carryforward, Name
Tax Credit Carryforward, Name [Domain]
Money Market Funds
Money Market Funds [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Total property and equipment
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Third amendment.
Third Amendment [Member]
Third amendment
Entity Interactive Data Current
Entity Interactive Data Current
Tax credit carryforwards
Tax Credit Carryforward, Amount
Entity Public Float
Entity Public Float
Number of shares, vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Letters of credit outstanding amount
Letters of Credit Outstanding, Amount
Number of non exclusive rights to gene editing targets.
Number of Non Exclusive Rights to Gene Editing Targets
Number of non-exclusive rights to gene editing targets
Operating lease not yet commenced minimum lease payments
Lessee Operating Lease Lease Not Yet Commenced Minimum Lease Payments
Lessee operating lease lease not yet commenced minimum lease payments.
2023
Lessee, Operating Lease, Liability, to be Paid, Year One
Leasehold Improvements
Leasehold Improvements [Member]
Proceeds from issuance initial public offering
Proceeds from initial public offering, net of issuance costs
Proceeds from Issuance Initial Public Offering
Local Phone Number
Local Phone Number
At-the-market offering
At The Market Offering [Member]
At the market offering
Gross unrecognized tax benefits
Balance at the beginning of the year
Balance at the end of the year
Unrecognized Tax Benefits
Computation of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Lease Contractual Term [Axis]
Number of shares, exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Operating lease, description
Lessee, Operating Lease, Description
IPO
IPO [Member]
Operating lease, existence of option to extend
Lessee, Operating Lease, Existence of Option to Extend [true false]
Number of shares, granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Other long-term liabilities
Other long-term liabilities
Other Liabilities, Noncurrent
Other Liabilities, Noncurrent, Total
Schedule of Change in Preferred Stock Purchase Right Liability
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Reverse stock split, conversion ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
Other Current Assets [Member]
Other Current Assets
Income Statement Location
Income Statement Location [Domain]
Number of shares, outstanding ending balance
Number of shares, outstanding beginning balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Beginning Balance, Shares
Ending Balance, Shares
Shares, Outstanding
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Accrued research and development costs
Accrued Research And Development Costs Current
Accrued research and development costs current.
Number of shares, outstanding beginning balance
Number of shares, outstanding ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Right-of-use assets obtained in exchange for operating lease liabilities resulting from modifications of existing leases
Right-of-use Assets Obtained in Exchange for Operating Lease Liabilities Resulting from Modifications of Existing Leases
Right-of-use assets obtained in exchange for operating lease liabilities resulting from modifications of existing leases.
Agreement with Financial Institution
Agreement With Financial Institution [Member]
Agreement with financial institution.
Document Fiscal Year Focus
Document Fiscal Year Focus
2024
Lessee, Operating Lease, Liability, to be Paid, Year Two
Net loss per share, basic
Net loss per share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Accounts payable and accrued and other liabilities
Increase Decrease In Accounts Payable And Accrued And Other Liabilities
Increase (Decrease) in accounts payable and accrued and other liabilities.
Employee Benefits
Compensation and Employee Benefit Plans [Text Block]
Assets
Assets [Abstract]
Net deferred tax assets
Deferred Tax Assets, Net
Reconciliation of cash, cash equivalents and restricted cash to the balance sheets:
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract]
Expected volatility, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Total prepaid expenses and other current assets
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Annual research license fees and Commercialization license fees.
Annual Research License Fees and Commercialization License Fees
Annual research license fees and Commercialization license fees
Temporary equity, series B preferred stock purchase right (liability) upon issuance of Series B convertible preferred stock
Temporary Equity Preferred Stock Purchase Right Liability Reversal Upon Issuance Of Convertible Securities
Temporary equity, preferred stock purchase right (liability) reversal upon issuance of convertible securities.
Financial Instrument
Financial Instrument [Axis]
Unvested Common Stock Upon Early Exercise of Common Stock Options
Unvested Common Stock Upon Early Exercise Of Common Stock Options [Member]
Unvested common stock upon early exercise of common stock options.
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Liabilities and Equity [Abstract]
Liabilities, convertible preferred stock and stockholders' equity
Property and Equipment, Net
Property, Plant and Equipment, Policy [Policy Text Block]
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Income Tax Authority
Income Tax Authority [Axis]
Net deferred tax asset
Deferred tax assets, net of valuation allowance
Deferred Tax Assets, Net of Valuation Allowance
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Current assets:
Assets, Current [Abstract]
Income Taxes [Table]
Income Taxes [Table]
Income taxes.
Significant Components of Deferred Tax Assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
License Maintenance Fees
License and Maintenance [Member]
Lease, Cost [Abstract]
Lease, Cost [Abstract]
Sale of preferred stock, net of issuance costs, Shares
Temporary equity, Issuance of Series B convertible preferred stock, net of issuance costs, Shares
Temporary Equity Stock Issued During Period Shares New Issues
Temporary equity stock issued during period shares new issues.
Lease term
Lessee, Operating Lease, Remaining Lease Term
Cover [Abstract]
Proceeds from secondary offering, net of issuance costs
Proceeds From Secondary Offering Net Of Issuance Costs
Proceeds from secondary offering net of issuance costs.
Unrecognized tax benefits, penalties and interest expense
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Product and Service
Product and Service [Domain]
Summary of Common Stock Reserved For Future Issuance
Summary Of Common Stock Reserved For Future Issuance Table [Text Block]
Summary of common stock reserved for future issuance.
2027
Lessee, Operating Lease, Liability, to be Paid, Year Five
Number of shares, vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Current liabilities:
Liabilities, Current [Abstract]
Cash, Cash Equivalents, Short-term Investments and Restricted Cash
Cash Cash Equivalents Short Term Investments And Restricted Cash Policy [Text Block]
Cash cash equivalents short term investments and restricted cash.
Maximum
Maximum [Member]
Unrealized loss on short-term investments
Unrealized loss on securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Net Cash Provided by (Used in) Investing Activities
Net cash provided by (used in) investing activities
Furniture and Fixtures
Furniture and Fixtures [Member]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Number of shares, exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Issuance of common stock upon exercise of stock option , Shares
Tenant improvements yet to receive from lessor.
Tenant Improvements Yet To Receive From Lessor
Tenant improvement allowances yet to receive
COVID-19 Pandemic
Unusual Or Infrequent Items Disclosure Policy [Text Block]
Unusual or infrequent items disclosure.
Significant Unobservable Inputs (Level 3)
Fair Value, Inputs, Level 3 [Member]
Summary of Share-based Compensation Expense
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Total accrued and other liabilities
Accounts Payable and Accrued Liabilities, Current
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Accrued property and equipment
Accrued Property And Equipment Liabilities Current
Accrued property and equipment liabilities current.
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of stock option
Segment Reporting
Segment Reporting, Policy [Policy Text Block]
Aggregate intrinsic value, vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Estimated useful lives of assets
Property, Plant and Equipment, Useful Life
Expense contribution plan
Defined Contribution Plan, Cost
Additional Lease Agreement
Additional Lease Agreement [Member]
Additional lease agreement.
After Year Two of the Agreement
After Year Two [Member]
After year two.
Common stock, shares authorized
Common Stock, Shares Authorized
Impairments
Impairments
Impairments.
Short-Term Debt, Type [Domain]
Trading Symbol
Trading Symbol
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Schedule of Short-term Investments
Debt Securities, Available-for-Sale [Table Text Block]
Deferred offering costs
Deferred Offering Costs Liabilities Current
Deferred offering costs liabilities current.
Title of Individual
Title of Individual [Domain]
Subsequent Event Type
Subsequent Event Type [Axis]
Other, net
Deferred Tax Assets, Other
Non-cash lease expense
Operating Lease, Right-of-Use Asset, Amortization Expense
Balance Sheet Location [Axis]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Deferred Offering Costs
Deferred Charges, Policy [Policy Text Block]
Follow On Offering of Stock
Follow On Offering of Stock [Member]
Follow on offering of stock.
Accounts payable
Accounts Payable, Current
Accounts Payable, Current, Total
Available for sale securities, Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Plan Name
Plan Name [Axis]
Title of Individual
Title of Individual [Axis]
Income tax benefit at statutory rates
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Fair value of common stock issued
Fair Value Of Common Stock Issued
Fair value of common stock issued.
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Common stock, par value
Common Stock, Par or Stated Value Per Share
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Variable lease expense
Variable Lease, Cost
Conversion of convertible preferred stock to common stock
Stock Issued During Period, Value, Conversion of Convertible Securities
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Number of shares, granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Weighted-average exercise price, granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Antidilutive securities excluded from computation of earnings per share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Investments
Cash and Cash Equivalents, Fair Value Disclosure